What are the bad side effects of phosphatidylserine?

Understanding Phosphatidylserine

Phosphatidylserine is a lipid substance that encapsulates the nerve cells in your brain, facilitating their communication. This supplement is popular for its potential role in enhancing cognitive abilities and memory, particularly as individuals age, by supporting cellular communication and optimizing glucose metabolism.

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With the natural levels of phosphatidylserine reducing as we grow older, supplementation becomes a choice for some to boost the phosphatidylserine concentration in their brain.

Phospholipids: Foundation of Phosphatidylserine

Phosphatidylserine belongs to the family of phospholipids, which are essential for constructing cell membranes in the brain, thus protecting the internal components of the cell from the external environment.

Phospholipids are lipid molecules that incorporate the mineral phosphorus. Phosphorus is a crucial element for the health of your bones, teeth, and genetic material (DNA).

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Exploring the Benefits of Phosphatidylserine

Phosphatidylserine, as a dietary supplement, purports to enhance:

• Memory retention.
• Overall cognitive performance.
• Focus and attention span.
• Alleviation of stress.
• Quality of sleep.

Moreover, it claims to address symptoms associated with:

• Lipid imbalances linked to ADHD.
• Depression and anxiety disorders.
• Alzheimer’s disease.

While the U.S. Food and Drug Administration (FDA) has not sanctioned phosphatidylserine for treating any medical ailment, it has affirmed that phosphatidylserine sourced from fish, soy lecithin, and sunflowers is generally considered safe (GRAS).

Phosphatidylserine for Anxiety: What You Should Know

It is suggested that phosphatidylserine aids in mitigating anxiety by reducing stress, stabilizing mood, and fostering relaxation. This supplement is believed to manage anxiety by maintaining cortisol levels, a hormone pivotal in stress response. However, it remains unapproved by the FDA as a treatment for anxiety.

Sources of Phosphatidylserine in Food

Phosphatidylserine is naturally present in a variety of foods, including:

• Soybeans.
• Fish.
• Eggs.
• Animal organs such as liver (chicken or beef).

Commercial phosphatidylserine supplements are typically derived from:

• Fish.
• Soy.
• Sunflowers.
• Cabbage.

Earlier formulations of these supplements included animal products such as cow’s brain (bovine cortex), but this practice was discontinued due to emerging safety concerns.

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