GREEN TEA - Uses, Side Effects, and More

Adcocks, C., Collin, P., and Buttle, D. J. Catechins from green tea (Camellia sinensis) inhibit bovine and human cartilage proteoglycan and type II collagen degradation in vitro. J Nutr. ;132(3):341-346. View abstract.

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Ahmed, S., Wang, N., Lalonde, M., Goldberg, V. M., and Haqqi, T. M. Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes. J Pharmacol.Exp.Ther. ;308(2):767-773. View abstract.

Al-Sowyan, N. S. Difference in leptin hormone response to nutritional status in normal adult male albino rats. Pak.J Biol.Sci. 1-15-;12(2):119-126. View abstract.

Alemdaroglu, N. C., Dietz, U., Wolffram, S., Spahn-Langguth, H., and Langguth, P. Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability. Biopharm.Drug Dispos. ;29(6):335-348. View abstract.

Alexopoulos, N., Vlachopoulos, C., Aznaouridis, K., Baou, K., Vasiliadou, C., Pietri, P., Xaplanteris, P., Stefanadi, E., and Stefanadis, C. The acute effect of green tea consumption on endothelial function in healthy individuals. Eur.J Cardiovasc.Prev.Rehabil. ;15(3):300-305. View abstract.

Ali, M., Afzal, M., Gubler, C. J., and Burka, J. F. A potent thromboxane formation inhibitor in green tea leaves. Prostaglandins Leukot.Essent.Fatty Acids ;40(4):281-283. View abstract.

Allen, N. E., Sauvaget, C., Roddam, A. W., Appleby, P., Nagano, J., Suzuki, G., Key, T. J., and Koyama, K. A prospective study of diet and prostate cancer in Japanese men. Cancer Causes Control ;15(9):911-920. View abstract.

Antonello, M., Montemurro, D., Bolognesi, M., Di, Pascoli M., Piva, A., Grego, F., Sticchi, D., Giuliani, L., Garbisa, S., and Rossi, G. P. Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts. Am.J Hypertens. ;20(12):-. View abstract.

Auvichayapat, P., Prapochanung, M., Tunkamnerdthai, O., Sripanidkulchai, B. O., Auvichayapat, N., Thinkhamrop, B., Kunhasura, S., Wongpratoom, S., Sinawat, S., and Hongprapas, P. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial. Physiol Behav 2-27-;93(3):486-491. View abstract.

Awadalla, H. I., Ragab, M. H., Bassuoni, M. W., Fayed, M. T., and Abbas, M. O. A pilot study of the role of green tea use on oral health. Int.J.Dent.Hyg. ;9(2):110-116. View abstract.

Babu, P. V. and Liu, D. Green tea catechins and cardiovascular health: an update. Curr.Med Chem. ;15(18):-. View abstract.

Babu, P. V., Sabitha, K. E., Srinivasan, P., and Shyamaladevi, C. S. Green tea attenuates diabetes induced Maillard-type fluorescence and collagen cross-linking in the heart of streptozotocin diabetic rats. Pharmacol.Res. ;55(5):433-440. View abstract.

Basu, A., Du, M., Sanchez, K., Leyva, M. J., Betts, N. M., Blevins, S., Wu, M., Aston, C. E., and Lyons, T. J. Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome. Nutrition ;27(2):206-213. View abstract.

Basu, A., Sanchez, K., Leyva, M. J., Wu, M., Betts, N. M., Aston, C. E., and Lyons, T. J. Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome. J Am.Coll.Nutr. ;29(1):31-40. View abstract.

Batista, Gde A., Cunha, C. L., Scartezini, M., von der, Heyde R., Bitencourt, M. G., and Melo, S. F. Prospective double-blind crossover study of Camellia sinensis (green tea) in dyslipidemias. Arq Bras.Cardiol. ;93(2):128-134. View abstract.

Belza, A., Toubro, S., and Astrup, A. The effect of caffeine, green tea and tyrosine on thermogenesis and energy intake. Eur.J Clin Nutr ;63(1):57-64. View abstract.

Bergman, J. and Schjott, J. Hepatitis caused by Lotus-f3? Basic Clin Pharmacol.Toxicol. ;104(5):414-416. View abstract.

Bertipaglia de Santana, M., Mandarino, M. G., Cardoso, J. R., Dichi, I., Dichi, J. B., Camargo, A. E., Fabris, B. A., Rodrigues, R. J., Fatel, E. C., Nixdorf, S. L., Simao, A. N., Cecchini, R., and Barbosa, D. S. Association between soy and green tea (Camellia sinensis) diminishes hypercholesterolemia and increases total plasma antioxidant potential in dyslipidemic subjects. Nutrition ;24(6):562-568. View abstract.

Bogdanski, P., Suliburska, J., Szulinska, M., Stepien, M., Pupek-Musialik, D., and Jablecka, A. Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutr.Res. ;32(6):421-427. View abstract.

Brown, A. L., Lane, J., Coverly, J., Stocks, J., Jackson, S., Stephen, A., Bluck, L., Coward, A., and Hendrickx, H. Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial. Br.J Nutr. ;101(6):886-894. View abstract.

Brown, A. L., Lane, J., Holyoak, C., Nicol, B., Mayes, A. E., and Dadd, T. Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial. Br.J.Nutr. ;106(12):-. View abstract.

Buscemi, S., Verga, S., Batsis, J. A., Donatelli, M., Tranchina, M. R., Belmonte, S., Mattina, A., Re, A., and Cerasola, G. Acute effects of coffee on endothelial function in healthy subjects. Eur.J Clin Nutr. ;64(5):483-489. View abstract.

Chan, C. C., Koo, M. W., Ng, E. H., Tang, O. S., Yeung, W. S., and Ho, P. C. Effects of Chinese green tea on weight, and hormonal and biochemical profiles in obese patients with polycystic ovary syndrome--a randomized placebo-controlled trial. J Soc Gynecol.Investig. ;13(1):63-68. View abstract.

Chiu, A. E., Chan, J. L., Kern, D. G., Kohler, S., Rehmus, W. E., and Kimball, A. B. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. ;31(7 Pt 2):855-860. View abstract.

Choan, E., Segal, R., Jonker, D., Malone, S., Reaume, N., Eapen, L., and Gallant, V. A prospective clinical trial of green tea for hormone refractory prostate cancer: an evaluation of the complementary/alternative therapy approach. Urol.Oncol. ;23(2):108-113. View abstract.

Choi, J. Y., Park, C. S., Kim, D. J., Cho, M. H., Jin, B. K., Pie, J. E., and Chung, W. G. Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology ;23(3):367-374. View abstract.

Choi, K. C., Jung, M. G., Lee, Y. H., Yoon, J. C., Kwon, S. H., Kang, H. B., Kim, M. J., Cha, J. H., Kim, Y. J., Jun, W. J., Lee, J. M., and Yoon, H. G. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res. 1-15-;69(2):583-592. View abstract.

Chow, H. H., Cai, Y., Alberts, D. S., Hakim, I., Dorr, R., Shahi, F., Crowell, J. A., Yang, C. S., and Hara, Y. Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol.Biomarkers Prev. ;10(1):53-58. View abstract.

Chow, H. H., Cai, Y., Hakim, I. A., Crowell, J. A., Shahi, F., Brooks, C. A., Dorr, R. T., Hara, Y., and Alberts, D. S. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res. 8-15-;9(9):-. View abstract.

Chow, H. H., Hakim, I. A., Vining, D. R., Crowell, J. A., Cordova, C. A., Chew, W. M., Xu, M. J., Hsu, C. H., Ranger-Moore, J., and Alberts, D. S. Effects of repeated green tea catechin administration on human cytochrome P450 activity. Cancer Epidemiol.Biomarkers Prev. ;15(12):-. View abstract.

Chow, H. H., Hakim, I. A., Vining, D. R., Crowell, J. A., Ranger-Moore, J., Chew, W. M., Celaya, C. A., Rodney, S. R., Hara, Y., and Alberts, D. S. Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals. Clin Cancer Res 6-15-;11(12):-. View abstract.

Chroscinska-Krawczyk, M., Ratnaraj, N., Patsalos, P. N., and Czuczwar, S. J. Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures. Pharmacol Rep. ;61(5):819-826. View abstract.

Clausen, T. Hormonal and pharmacological modification of plasma potassium homeostasis. Fundam.Clin Pharmacol ;24(5):595-605. View abstract.

Conen, D., Chiuve, S. E., Everett, B. M., Zhang, S. M., Buring, J. E., and Albert, C. M. Caffeine consumption and incident atrial fibrillation in women. Am J Clin Nutr ;92(3):509-514. View abstract.

Cronin JR. Green tea extract stokes thermogenesis. Alternative and Complementary Therapies ;296-300.

Das, A., Banik, N. L., and Ray, S. K. Flavonoids activated caspases for apoptosis in human glioblastoma T98G and U87MG cells but not in human normal astrocytes. Cancer 1-1-;116(1):164-176. View abstract.

Del, Rio D., Calani, L., Cordero, C., Salvatore, S., Pellegrini, N., and Brighenti, F. Bioavailability and catabolism of green tea flavan-3-ols in humans. Nutrition 1-14-; View abstract.

Devika, P. T. and Stanely Mainzen, Prince P. (-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study. Pharmacol.Res. ;57(5):351-357. View abstract.

Di, Pierro F., Menghi, A. B., Barreca, A., Lucarelli, M., and Calandrelli, A. Greenselect Phytosome as an adjunct to a low-calorie diet for treatment of obesity: a clinical trial. Altern.Med Rev. ;14(2):154-160. View abstract.

Diepvens, K., Kovacs, E. M., Vogels, N., and Westerterp-Plantenga, M. S. Metabolic effects of green tea and of phases of weight loss. Physiol Behav 1-30-;87(1):185-191. View abstract.

Donovan, J. L., Devane, C. L., Chavin, K. D., Oates, J. C., Njoku, C., Patrick, K. S., Fiorini, R. N., and Markowitz, J. S. Oral administration of a decaffeinated green tea (Camellia sinensis) extract did not alter urinary 8-epi-prostaglandin F(2 alpha), a biomarker for in-vivo lipid peroxidation. J Pharm Pharmacol ;57(10):-. View abstract.

Du, X., Huang, X., Huang, C., Wang, Y., and Zhang, Y. Epigallocatechin-3-gallate (EGCG) enhances the therapeutic activity of a dental adhesive. J.Dent. ;40(6):485-492. View abstract.

Dufresne CJ and Farnworth ER. A review of latest research findings on the health promotion properties of tea. Journal of Nutritional Biochemistry ;12:404-421.

Dulloo, A. G. and Miller, D. S. The thermogenic properties of ephedrine/methylxanthine mixtures: animal studies. Am J Clin Nutr ;43(3):388-394. View abstract.

Dulloo, A. G., Seydoux, J., Girardier, L., Chantre, P., and Vandermander, J. Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. Int J Obes.Relat Metab Disord. ;24(2):252-258. View abstract.

Dunne, E. F., Friedman, A., Datta, S. D., Markowitz, L. E., and Workowski, K. A. Updates on human papillomavirus and genital warts and counseling messages from the Sexually Transmitted Diseases Treatment Guidelines. Clin.Infect.Dis. ;53 Suppl 3:S143-S152. View abstract.

Eichenberger, P., Colombani, P. C., and Mettler, S. Effects of 3-week consumption of green tea extracts on whole-body metabolism during cycling exercise in endurance-trained men. Int J Vitam.Nutr.Res. ;79(1):24-33. View abstract.

Eichenberger, P., Mettler, S., Arnold, M., and Colombani, P. C. No effects of three-week consumption of a green tea extract on time trial performance in endurance-trained men. Int J Vitam.Nutr.Res. ;80(1):54-64. View abstract.

Engdal, S. and Nilsen, O. G. In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients. Phytother.Res. ;23(7):906-912. View abstract.

Erba, D., Riso, P., Bordoni, A., Foti, P., Biagi, P. L., and Testolin, G. Effectiveness of moderate green tea consumption on antioxidative status and plasma lipid profile in humans. J Nutr Biochem ;16(3):144-149. View abstract.

Ernest, D., Chia, M., and Corallo, C. E. Profound hypokalaemia due to Nurofen Plus and Red Bull misuse. Crit Care Resusc. ;12(2):109-110. View abstract.

Federico, A., Tiso, A., and Loguercio, C. A case of hepatotoxicity caused by green tea. Free Radic.Biol Med 8-1-;43(3):474. View abstract.

Frank, J., George, T. W., Lodge, J. K., Rodriguez-Mateos, A. M., Spencer, J. P., Minihane, A. M., and Rimbach, G. Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men. J Nutr ;139(1):58-62. View abstract.

Freese, R., Basu, S., Hietanen, E., Nair, J., Nakachi, K., Bartsch, H., and Mutanen, M. Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females. Eur.J Nutr. ;38(3):149-157. View abstract.

Fukino, Y., Ikeda, A., Maruyama, K., Aoki, N., Okubo, T., and Iso, H. Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities. Eur.J Clin Nutr ;62(8):953-960. View abstract.

Fukino, Y., Shimbo, M., Aoki, N., Okubo, T., and Iso, H. Randomized controlled trial for an effect of green tea consumption on insulin resistance and inflammation markers. J Nutr Sci Vitaminol.(Tokyo) ;51(5):335-342. View abstract.

Fukushima, Y., Ohie, T., Yonekawa, Y., Yonemoto, K., Aizawa, H., Mori, Y., Watanabe, M., Takeuchi, M., Hasegawa, M., Taguchi, C., and Kondo, K. Coffee and green tea as a large source of antioxidant polyphenols in the Japanese population. J Agric.Food Chem. 2-25-;57(4):-. View abstract.

Gao, Y. T., McLaughlin, J. K., Blot, W. J., Ji, B. T., Dai, Q., and Fraumeni, J. F., Jr. Reduced risk of esophageal cancer associated with green tea consumption. J Natl.Cancer Inst. 6-1-;86(11):855-858. View abstract.

Gawande, S., Kale, A., and Kotwal, S. Effect of nutrient mixture and black grapes on the pharmacokinetics of orally administered (-)epigallocatechin-3-gallate from green tea extract: a human study. Phytother.Res. ;22(6):802-808. View abstract.

Gregersen, N. T., Bitz, C., Krog-Mikkelsen, I., Hels, O., Kovacs, E. M., Rycroft, J. A., Frandsen, E., Mela, D. J., and Astrup, A. Effect of moderate intakes of different tea catechins and caffeine on acute measures of energy metabolism under sedentary conditions. Br.J Nutr. ;102(8):-. View abstract.

Gronroos, N. N. and Alonso, A. Diet and risk of atrial fibrillation - epidemiologic and clinical evidence -. Circ.J ;74(10):-. View abstract.

Gross, G. [Polyphenon E. A new topical therapy for condylomata acuminata]. Hautarzt ;59(1):31-35. View abstract.

Gross, G., Meyer, K. G., Pres, H., Thielert, C., Tawfik, H., and Mescheder, A. A randomized, double-blind, four-arm parallel-group, placebo-controlled Phase II/III study to investigate the clinical efficacy of two galenic formulations of Polyphenon E in the treatment of external genital warts. J Eur.Acad.Dermatol.Venereol. ;21(10):-. View abstract.

Hakim, I. A., Chow, H. H., and Harris, R. B. Green tea consumption is associated with decreased DNA damage among GSTM1-positive smokers regardless of their hOGG1 genotype. J Nutr. ;138(8):S-S. View abstract.

Hakim, I. A., Harris, R. B., Brown, S., Chow, H. H., Wiseman, S., Agarwal, S., and Talbot, W. Effect of increased tea consumption on oxidative DNA damage among smokers: a randomized controlled study. J.Nutr. ;133(10):S-S. View abstract.

Hakim, I. A., Harris, R. B., Chow, H. H., Dean, M., Brown, S., and Ali, I. U. Effect of a 4-month tea intervention on oxidative DNA damage among heavy smokers: role of glutathione S-transferase genotypes. Cancer Epidemiol.Biomarkers Prev. ;13(2):242-249. View abstract.

Hasani-Ranjbar, S., Nayebi, N., Moradi, L., Mehri, A., Larijani, B., and Abdollahi, M. The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. Curr.Pharm.Des ;16(26):-. View abstract.

Hatano, B., Kojima, A., Sata, T., and Katano, H. Virus detection using Viro-Adembeads, a rapid capture system for viruses, and plaque assay in intentionally virus-contaminated beverages. Jpn.J Infect.Dis. ;63(1):52-54. View abstract.

Hattori, M., Kusumoto, I. T., Namba, T., Ishigami, T., and Hara, Y. Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans. Chem.Pharm Bull.(Tokyo) ;38(3):717-720. View abstract.

Hauber, I., Hohenberg, H., Holstermann, B., Hunstein, W., and Hauber, J. The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection. Proc.Natl.Acad.Sci.U.S.A 6-2-;106(22):-. View abstract.

He, Y. H. and Kies, C. Green and black tea consumption by humans: impact on polyphenol concentrations in feces, blood and urine. Plant Foods Hum.Nutr. ;46(3):221-229. View abstract.

Heinrich, U., Moore, C. E., De, Spirt S., Tronnier, H., and Stahl, W. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women. J.Nutr. ;141(6):-. View abstract.

Henning, S. M., Aronson, W., Niu, Y., Conde, F., Lee, N. H., Seeram, N. P., Lee, R. P., Lu, J., Harris, D. M., Moro, A., Hong, J., Pak-Shan, L., Barnard, R. J., Ziaee, H. G., Csathy, G., Go, V. L., Wang, H., and Heber, D. Tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. J Nutr ;136(7):-. View abstract.

Henning, S. M., Niu, Y., Lee, N. H., Thames, G. D., Minutti, R. R., Wang, H., Go, V. L., and Heber, D. Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. Am J Clin Nutr ;80(6):-. View abstract.

Henrotin, Y., Lambert, C., Couchourel, D., Ripoll, C., and Chiotelli, E. Nutraceuticals: do they represent a new era in the management of osteoarthritis? - a narrative review from the lessons taken with five products. Osteoarthritis.Cartilage. ;19(1):1-21. View abstract.

Hirano-Ohmori, R., Takahashi, R., Momiyama, Y., Taniguchi, H., Yonemura, A., Tamai, S., Umegaki, K., Nakamura, H., Kondo, K., and Ohsuzu, F. Green tea consumption and serum malondialdehyde-modified LDL concentrations in healthy subjects. J Am Coll.Nutr ;24(5):342-346. View abstract.

Hirao, K., Yumoto, H., Nakanishi, T., Mukai, K., Takahashi, K., Takegawa, D., and Matsuo, T. Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. Life Sci. 4-24-;86(17-18):654-660. View abstract.

Hirasawa, M., Takada, K., Makimura, M., and Otake, S. Improvement of periodontal status by green tea catechin using a local delivery system: a clinical pilot study. J Periodontal Res ;37(6):433-438. View abstract.

Horiba, N., Maekawa, Y., Ito, M., Matsumoto, T., and Nakamura, H. A pilot study of Japanese green tea as a medicament: antibacterial and bactericidal effects. J Endod. ;17(3):122-124. View abstract.

Hsu, C. H., Liao, Y. L., Lin, S. C., Tsai, T. H., Huang, C. J., and Chou, P. Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial. Altern.Med.Rev. ;16(2):157-163. View abstract.

Hsu, C. H., Tsai, T. H., Kao, Y. H., Hwang, K. C., Tseng, T. Y., and Chou, P. Effect of green tea extract on obese women: a randomized, double-blind, placebo-controlled clinical trial. Clin Nutr ;27(3):363-370. View abstract.

Ichinose, T., Nomura, S., Someya, Y., Akimoto, S., Tachiyashiki, K., and Imaizumi, K. Effect of endurance training supplemented with green tea extract on substrate metabolism during exercise in humans. Scand.J Med Sci.Sports 3-10-; View abstract.

Inami, S., Takano, M., Yamamoto, M., Murakami, D., Tajika, K., Yodogawa, K., Yokoyama, S., Ohno, N., Ohba, T., Sano, J., Ibuki, C., Seino, Y., and Mizuno, K. Tea catechin consumption reduces circulating oxidized low-density lipoprotein. Int Heart J ;48(6):725-732. View abstract.

Izzo, A. A. and Ernst, E. Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs ;69(13):-. View abstract.

Janjua, R., Munoz, C., Gorell, E., Rehmus, W., Egbert, B., Kern, D., and Chang, A. L. A two-year, double-blind, randomized placebo-controlled trial of oral green tea polyphenols on the long-term clinical and histologic appearance of photoaging skin. Dermatol.Surg. ;35(7):-. View abstract.

Jankun, J., Selman, S. H., Swiercz, R., and Skrzypczak-Jankun, E. Why drinking green tea could prevent cancer. Nature 6-5-;387():561. View abstract.

Javaid, A. and Bonkovsky, H. L. Hepatotoxicity due to extracts of Chinese green tea (Camellia sinensis): a growing concern. J Hepatol ;45(2):334-335. View abstract.

Ji, B. T., Chow, W. H., Hsing, A. W., McLaughlin, J. K., Dai, Q., Gao, Y. T., Blot, W. J., and Fraumeni, J. F., Jr. Green tea consumption and the risk of pancreatic and colorectal cancers. Int J Cancer 1-27-;70(3):255-258. View abstract.

Josic, J., Olsson, A. T., Wickeberg, J., Lindstedt, S., and Hlebowicz, J. Does green tea affect postprandial glucose, insulin and satiety in healthy subjects: a randomized controlled trial. Nutr.J. ;9:63. View abstract.

Jowko, E., Sacharuk, J., Balasinska, B., Ostaszewski, P., Charmas, M., and Charmas, R. Green tea extract supplementation gives protection against exercise-induced oxidative damage in healthy men. Nutr.Res. ;31(11):813-821. View abstract.

Jurgens, T. M., Whelan, A. M., Killian, L., Doucette, S., Kirk, S., and Foy, E. Green tea for weight loss and weight maintenance in overweight or obese adults. Cochrane.Database.Syst.Rev. ;12:CD. View abstract.

Kalus, U., Kiesewetter, H., and Radtke, H. Effect of CYSTUS052 and green tea on subjective symptoms in patients with infection of the upper respiratory tract. Phytother.Res. ;24(1):96-100. View abstract.

Karth, A., Holoshitz, N., Kavinsky, C. J., Trohman, R., and McBride, B. F. A case report of atrial fibrillation potentially induced by hydroxycut: a multicomponent dietary weight loss supplement devoid of sympathomimetic amines. J.Pharm.Pract. ;23(3):245-249. View abstract.

Katiyar, S. K., Matsui, M. S., Elmets, C. A., and Mukhtar, H. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem.Photobiol. ;69(2):148-153. View abstract.

Kato, M. T., Leite, A. L., Hannas, A. R., and Buzalaf, M. A. Gels containing MMP inhibitors prevent dental erosion in situ. J Dent.Res. ;89(5):468-472. View abstract.

Kikuchi, N., Ohmori, K., Shimazu, T., Nakaya, N., Kuriyama, S., Nishino, Y., Tsubono, Y., and Tsuji, I. No association between green tea and prostate cancer risk in Japanese men: the Ohsaki Cohort Study. Br.J Cancer 8-7-;95(3):371-373. View abstract.

Kim, W., Jeong, M. H., Cho, S. H., Yun, J. H., Chae, H. J., Ahn, Y. K., Lee, M. C., Cheng, X., Kondo, T., Murohara, T., and Kang, J. C. Effect of green tea consumption on endothelial function and circulating endothelial progenitor cells in chronic smokers. Circ.J ;70(8):-. View abstract.

Komatsu, T., Nakamori, M., Komatsu, K., Hosoda, K., Okamura, M., Toyama, K., Ishikura, Y., Sakai, T., Kunii, D., and Yamamoto, S. Oolong tea increases energy metabolism in Japanese females. J Med Invest ;50(3-4):170-175. View abstract.

Kristen, A. V., Lehrke, S., Buss, S., Mereles, D., Steen, H., Ehlermann, P., Hardt, S., Giannitsis, E., Schreiner, R., Haberkorn, U., Schnabel, P. A., Linke, R. P., Rocken, C., Wanker, E. E., Dengler, T. J., Altland, K., and Katus, H. A. Green tea halts progression of cardiac transthyretin amyloidosis: an observational report. Clin.Res.Cardiol. ;101(10):805-813. View abstract.

Kuo, Y. C., Yu, C. L., Liu, C. Y., Wang, S. F., Pan, P. C., Wu, M. T., Ho, C. K., Lo, Y. S., Li, Y., and Christiani, D. C. A population-based, case-control study of green tea consumption and leukemia risk in southwestern Taiwan. Cancer Causes Control ;20(1):57-65. View abstract.

Kurahashi, N., Sasazuki, S., Iwasaki, M., Inoue, M., and Tsugane, S. Green tea consumption and prostate cancer risk in Japanese men: a prospective study. Am J Epidemiol. 1-1-;167(1):71-77. View abstract.

Kuriyama, S. The relation between green tea consumption and cardiovascular disease as evidenced by epidemiological studies. J Nutr. ;138(8):S-S. View abstract.

Kushima, Y., Iida, K., Nagaoka, Y., Kawaratani, Y., Shirahama, T., Sakaguchi, M., Baba, K., Hara, Y., and Uesato, S. Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biol.Pharm.Bull. ;32(5):899-904. View abstract.

Kushiyama, M., Shimazaki, Y., Murakami, M., and Yamashita, Y. Relationship between intake of green tea and periodontal disease. J Periodontol. ;80(3):372-377. View abstract.

Lang, M., Henson, R., Braconi, C., and Patel, T. Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells. Liver Int ;29(5):670-677. View abstract.

Langley, P. C. A cost-effectiveness analysis of sinecatechins in the treatment of external genital warts. J.Med.Econ. ;13(1):1-7. View abstract.

Laurie, S. A., Miller, V. A., Grant, S. C., Kris, M. G., and Ng, K. K. Phase I study of green tea extract in patients with advanced lung cancer. Cancer Chemother.Pharmacol. ;55(1):33-38. View abstract.

Levites, Y., Amit, T., Mandel, S., and Youdim, M. B. Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J ;17(8):952-954. View abstract.

Li, G. X., Chen, Y. K., Hou, Z., Xiao, H., Jin, H., Lu, G., Lee, M. J., Liu, B., Guan, F., Yang, Z., Yu, A., and Yang, C. S. Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro. Carcinogenesis ;31(5):902-910. View abstract.

Li, R., Huang, Y. G., Fang, D., and Le, W. D. (-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury. J Neurosci.Res. 12-1-;78(5):723-731. View abstract.

Liatsos, G. D., Moulakakis, A., Ketikoglou, I., and Klonari, S. Possible green tea-induced thrombotic thrombocytopenic purpura. Am.J Health Syst.Pharm. 4-1-;67(7):531-534. View abstract.

Lin, C. L., Chen, T. F., Chiu, M. J., Way, T. D., and Lin, J. K. Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation. Neurobiol.Aging ;30(1):81-92. View abstract.

Lonac, M. C., Richards, J. C., Schweder, M. M., Johnson, T. K., and Bell, C. Influence of Short-Term Consumption of the Caffeine-Free, Epigallocatechin-3-Gallate Supplement, Teavigo, on Resting Metabolism and the Thermic Effect of Feeding. Obesity.(Silver.Spring) 8-19-; View abstract.

Lopez-Garcia, E., Rodriguez-Artalejo, F., Rexrode, K. M., Logroscino, G., Hu, F. B., and van Dam, R. M. Coffee consumption and risk of stroke in women. Circulation 3-3-;119(8):-. View abstract.

MacKenzie, T., Comi, R., Sluss, P., Keisari, R., Manwar, S., Kim, J., Larson, R., and Baron, J. A. Metabolic and hormonal effects of caffeine: randomized, double-blind, placebo-controlled crossover trial. Metabolism ;56(12):-. View abstract.

Maeda-Yamamoto, M., Ema, K., Monobe, M., Shibuichi, I., Shinoda, Y., Yamamoto, T., and Fujisawa, T. The efficacy of early treatment of seasonal allergic rhinitis with benifuuki green tea containing O-methylated catechin before pollen exposure: an open randomized study. Allergol.Int ;58(3):437-444. View abstract.

Mahmood, T., Akhtar, N., Khan, B. A., Shoaib Khan, H. M., and Saeed, T. Changes in skin mechanical properties after long-term application of cream containing green tea extract. Aging Clin.Exp.Res. ;23(5-6):333-336. View abstract.

Maki, K. C., Reeves, M. S., Farmer, M., Yasunaga, K., Matsuo, N., Katsuragi, Y., Komikado, M., Tokimitsu, I., Wilder, D., Jones, F., Blumberg, J. B., and Cartwright, Y. Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults. J Nutr ;139(2):264-270. View abstract.

Martinez-Sierra, C., Rendon, Unceta P., and Martin, Herrera L. [Acute hepatitis after green tea ingestion]. Med Clin (Barc.) 6-17-;127(3):119. View abstract.

Matsumoto, K., Yamada, H., Takuma, N., Niino, H., and Sagesaka, Y. M. Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial. BMC.Complement Altern.Med. ;11:15. View abstract.

Matsuyama, T., Tanaka, Y., Kamimaki, I., Nagao, T., and Tokimitsu, I. Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children. Obesity.(Silver.Spring) ;16(6):-. View abstract.

Melgarejo, E., Medina, M. A., Sanchez-Jimenez, F., and Urdiales, J. L. Epigallocatechin gallate reduces human monocyte mobility and adhesion in vitro. Br.J Pharmacol. ;158(7):-. View abstract.

Meltzer, S. M., Monk, B. J., and Tewari, K. S. Green tea catechins for treatment of external genital warts. Am J Obstet.Gynecol. ;200(3):233-237. View abstract.

Miller, R. J., Jackson, K. G., Dadd, T., Mayes, A. E., Brown, A. L., and Minihane, A. M. The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract. Br.J.Nutr. ;105(8):-. View abstract.

Miller, R. J., Jackson, K. G., Dadd, T., Mayes, A. E., Brown, A. L., Lovegrove, J. A., and Minihane, A. M. The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion. Mol.Nutr.Food Res. ;56(6):966-975. View abstract.

Miller, R. J., Jackson, K. G., Dadd, T., Nicol, B., Dick, J. L., Mayes, A. E., Brown, A. L., and Minihane, A. M. A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins. Eur.J.Nutr. ;51(1):47-55. View abstract.

Mnich, C. D., Hoek, K. S., Virkki, L. V., Farkas, A., Dudli, C., Laine, E., Urosevic, M., and Dummer, R. Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls. Exp Dermatol. ;18(1):69-77. View abstract.

Moisey, L. L., Robinson, L. E., and Graham, T. E. Consumption of caffeinated coffee and a high carbohydrate meal affects postprandial metabolism of a subsequent oral glucose tolerance test in young, healthy males. Br.J Nutr. ;103(6):833-841. View abstract.

Molinari, M., Watt, K. D., Kruszyna, T., Nelson, R., Walsh, M., Huang, W. Y., Nashan, B., and Peltekian, K. Acute liver failure induced by green tea extracts: case report and review of the literature. Liver Transpl. ;12(12):-. View abstract.

Mukoyama, A., Ushijima, H., Nishimura, S., Koike, H., Toda, M., Hara, Y., and Shimamura, T. Inhibition of rotavirus and enterovirus infections by tea extracts. Jpn.J Med.Sci Biol. ;44(4):181-186. View abstract.

Mulder, T. P., Rietveld, A. G., and Van Amelsvoort, J. M. Consumption of both black tea and green tea results in an increase in the excretion of hippuric acid into urine. Am.J.Clin Nutr. ;81(1 Suppl):256S-260S. View abstract.

Muller, N., Ellinger, S., Alteheld, B., Ulrich-Merzenich, G., Berthold, H. K., Vetter, H., and Stehle, P. Bolus ingestion of white and green tea increases the concentration of several flavan-3-ols in plasma, but does not affect markers of oxidative stress in healthy non-smokers. Mol.Nutr.Food Res. 6-10-; View abstract.

Myung, S. K., Bae, W. K., Oh, S. M., Kim, Y., Ju, W., Sung, J., Lee, Y. J., Ko, J. A., Song, J. I., and Choi, H. J. Green tea consumption and risk of stomach cancer: a meta-analysis of epidemiologic studies. Int J Cancer 2-1-;124(3):670-677. View abstract.

Nagao, T., Hase, T., and Tokimitsu, I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity.(Silver.Spring) ;15(6):-. View abstract.

Nagao, T., Komine, Y., Soga, S., Meguro, S., Hase, T., Tanaka, Y., and Tokimitsu, I. Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Am J Clin Nutr ;81(1):122-129. View abstract.

Nagao, T., Meguro, S., Hase, T., Otsuka, K., Komikado, M., Tokimitsu, I., Yamamoto, T., and Yamamoto, K. A catechin-rich beverage improves obesity and blood glucose control in patients with type 2 diabetes. Obesity.(Silver.Spring) ;17(2):310-317. View abstract.

Nagata, C., Kabuto, M., and Shimizu, H. Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women. Nutr Cancer ;30(1):21-24. View abstract.

Nakachi, K., Suemasu, K., Suga, K., Takeo, T., Imai, K., and Higashi, Y. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res ;89(3):254-261. View abstract.

Nakagawa, K., Okuda, S., and Miyazawa, T. Dose-dependent incorporation of tea catechins, (-)-epigallocatechin-3- gallate and (-)-epigallocatechin, into human plasma. Biosci.Biotechnol.Biochem ;61(12):-. View abstract.

Nakayama, M., Suzuki, K., Toda, M., Okubo, S., Hara, Y., and Shimamura, T. Inhibition of the infectivity of influenza virus by tea polyphenols. Antiviral Res. ;21(4):289-299. View abstract.

Nance, C. L., Siwak, E. B., and Shearer, W. T. Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy. J Allergy Clin Immunol. ;123(2):459-465. View abstract.

Nantz, M. P., Rowe, C. A., Bukowski, J. F., and Percival, S. S. Standardized capsule of Camellia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo-controlled study. Nutrition ;25(2):147-154. View abstract.

Netsch, M. I., Gutmann, H., Schmidlin, C. B., Aydogan, C., and Drewe, J. Induction of CYP1A by green tea extract in human intestinal cell lines. Planta Med ;72(6):514-520. View abstract.

Nguyen, M. M., Ahmann, F. R., Nagle, R. B., Hsu, C. H., Tangrea, J. A., Parnes, H. L., Sokoloff, M. H., Gretzer, M. B., and Chow, H. H. Randomized, double-blind, placebo-controlled trial of polyphenon E in prostate cancer patients before prostatectomy: evaluation of potential chemopreventive activities. Cancer Prev.Res.(Phila) ;5(2):290-298. View abstract.

Ogunleye, A. A., Xue, F., and Michels, K. B. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res.Treat. ;119(2):477-484. View abstract.

Okada, N., Tanabe, H., Tazoe, H., Ishigami, Y., Fukutomi, R., Yasui, K., and Isemura, M. Differentiation-associated alteration in sensitivity to apoptosis induced by (-)-epigallocatechin-3-O-gallate in HL-60 cells. Biomed.Res. ;30(4):201-206. View abstract.

Orozco-Gregorio, H., Mota-Rojas, D., Bonilla-Jaime, H., Trujillo-Ortega, M. E., Becerril-Herrera, M., Hernandez-Gonzalez, R., and Villanueva-Garcia, D. Effects of administration of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia. Am.J Vet.Res. ;71(10):-. View abstract.

Ostrowska, J. and Skrzydlewska, E. The comparison of effect of catechins and green tea extract on oxidative modification of LDL in vitro. Adv Med Sci ;51:298-303. View abstract.

Otake, S., Makimura, M., Kuroki, T., Nishihara, Y., and Hirasawa, M. Anticaries effects of polyphenolic compounds from Japanese green tea. Caries Res ;25(6):438-443. View abstract.

Otera, H., Tada, K., Sakurai, T., Hashimoto, K., and Ikeda, A. Hypersensitivity pneumonitis associated with inhalation of catechin-rich green tea extracts. Respiration ;82(4):388-392. View abstract.

Oyama, J., Maeda, T., Sasaki, M., Kozuma, K., Ochiai, R., Tokimitsu, I., Taguchi, S., Higuchi, Y., and Makino, N. Green tea catechins improve human forearm vascular function and have potent anti-inflammatory and anti-apoptotic effects in smokers. Intern.Med. ;49(23):-. View abstract.

Pan, T., Fei, J., Zhou, X., Jankovic, J., and Le, W. Effects of green tea polyphenols on dopamine uptake and on MPP+ -induced dopamine neuron injury. Life Sci. 1-17-;72(9):-. View abstract.

Panza, V. S., Wazlawik, E., Ricardo, Schutz G., Comin, L., Hecht, K. C., and da Silva, E. L. Consumption of green tea favorably affects oxidative stress markers in weight-trained men. Nutrition ;24(5):433-442. View abstract.

Papparella, I., Ceolotto, G., Montemurro, D., Antonello, M., Garbisa, S., Rossi, G., and Semplicini, A. Green tea attenuates angiotensin II-induced cardiac hypertrophy in rats by modulating reactive oxygen species production and the Src/epidermal growth factor receptor/Akt signaling pathway. J Nutr. ;138(9):-. View abstract.

Park, S. K., Jung, I. C., Lee, W. K., Lee, Y. S., Park, H. K., Go, H. J., Kim, K., Lim, N. K., Hong, J. T., Ly, S. Y., and Rho, S. S. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J.Med.Food ;14(4):334-343. View abstract.

Pecorari, M., Villano, D., Testa, M. F., Schmid, M., and Serafini, M. Biomarkers of antioxidant status following ingestion of green teas at different polyphenol concentrations and antioxidant capacity in human volunteers. Mol.Nutr.Food Res. ;54 Suppl 2:S278-S283. View abstract.

Perera, V., Gross, A. S., and McLachlan, A. J. Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma. Biomed.Chromatogr. ;24(10):-. View abstract.

Pietta, P., Simonetti, P., Gardana, C., Brusamolino, A., Morazzoni, P., and Bombardelli, E. Relationship between rate and extent of catechin absorption and plasma antioxidant status. Biochem Mol.Biol Int. ;46(5):895-903. View abstract.

Rasheed, Z., Anbazhagan, A. N., Akhtar, N., Ramamurthy, S., Voss, F. R., and Haqqi, T. M. Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes. Arthritis Res.Ther. ;11(3):R71. View abstract.

Reis, J. P., Loria, C. M., Steffen, L. M., Zhou, X., van, Horn L., Siscovick, D. S., Jacobs, D. R., Jr., and Carr, J. J. Coffee, decaffeinated coffee, caffeine, and tea consumption in young adulthood and atherosclerosis later in life: the CARDIA study. Arterioscler.Thromb.Vasc.Biol ;30(10):-. View abstract.

Renouf, M., Guy, P., Marmet, C., Longet, K., Fraering, A. L., Moulin, J., Barron, D., Dionisi, F., Cavin, C., Steiling, H., and Williamson, G. Plasma appearance and correlation between coffee and green tea metabolites in human subjects. Br.J Nutr. 8-9-;1-6. View abstract.

Richards, J. C., Lonac, M. C., Johnson, T. K., Schweder, M. M., and Bell, C. Epigallocatechin-3-gallate Increases Maximal Oxygen Uptake in Adult Humans. Med Sci.Sports Exerc. 11-27-; View abstract.

Rigato, I., Blarasin, L., and Kette, F. Severe hypokalemia in 2 young bicycle riders due to massive caffeine intake. Clin J Sport Med. ;20(2):128-130. View abstract.

Rizvi, S. I., Jha, R., and Pandey, K. B. Activation of erythrocyte plasma membrane redox system provides a useful method to evaluate antioxidant potential of plant polyphenols. Methods Mol.Biol. ;594:341-348. View abstract.

Rohde, J., Jacobsen, C., and Kromann-Andersen, H. [Toxic hepatitis triggered by green tea]. Ugeskr.Laeger 1-17-;173(3):205-206. View abstract.

Roomi, M. W., Monterrey, J. C., Kalinovsky, T., Rath, M., and Niedzwiecki, A. Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines. Oncol.Rep. ;24(3):747-757. View abstract.

Rosenbaum, C. C., O'Mathuna, D. P., Chavez, M., and Shields, K. Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis. Altern.Ther.Health Med. ;16(2):32-40. View abstract.

Rowe, C. A., Nantz, M. P., Bukowski, J. F., and Percival, S. S. Specific formulation of Camellia sinensis prevents cold and flu symptoms and enhances gamma,delta T cell function: a randomized, double-blind, placebo-controlled study. J Am Coll.Nutr ;26(5):445-452. View abstract.

Ryu, O. H., Lee, J., Lee, K. W., Kim, H. Y., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., Choi, D. S., and Choi, K. M. Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Res.Clin Pract. ;71(3):356-358. View abstract.

Sagesaka-Mitane, Y., Miwa, M., and Okada, S. Platelet aggregation inhibitors in hot water extract of green tea. Chem Pharm Bull.(Tokyo) ;38(3):790-793. View abstract.

Sakamoto, O., Saita, N., Yamasaki, H., Tamanoi, M., and Ando, M. Pulmonary granulomatosis caused by aspirated green tea. Chest ;106(1):308-309. View abstract.

Sarma, D. N., Barrett, M. L., Chavez, M. L., Gardiner, P., Ko, R., Mahady, G. B., Marles, R. J., Pellicore, L. S., Giancaspro, G. I., and Low, Dog T. Safety of green tea extracts : a systematic review by the US Pharmacopeia. Drug Saf ;31(6):469-484. View abstract.

Sasazuki, S., Kodama, H., Yoshimasu, K., Liu, Y., Washio, M., Tanaka, K., Tokunaga, S., Kono, S., Arai, H., Doi, Y., Kawano, T., Nakagaki, O., Takada, K., Koyanagi, S., Hiyamuta, K., Nii, T., Shirai, K., Ideishi, M., Arakawa, K., Mohri, M., and Takeshita, A. Relation between green tea consumption and the severity of coronary atherosclerosis among Japanese men and women. Ann.Epidemiol. ;10(6):401-408. View abstract.

Sato, Y., Nakatsuka, H., Watanabe, T., Hisamichi, S., Shimizu, H., Fujisaku, S., Ichinowatari, Y., Ida, Y., Suda, S., Kato, K., and . Possible contribution of green tea drinking habits to the prevention of stroke. Tohoku J Exp Med ;157(4):337-343. View abstract.

Scholey, A., Downey, L. A., Ciorciari, J., Pipingas, A., Nolidin, K., Finn, M., Wines, M., Catchlove, S., Terrens, A., Barlow, E., Gordon, L., and Stough, C. Acute neurocognitive effects of epigallocatechin gallate (EGCG). Appetite ;58(2):767-770. View abstract.

Serafini, M., Ghiselli, A., and Ferro-Luzzi, A. In vivo antioxidant effect of green and black tea in man. Eur.J Clin Nutr. ;50(1):28-32. View abstract.

Shen, C. L., Chyu, M. C., Yeh, J. K., Zhang, Y., Pence, B. C., Felton, C. K., Brismee, J. M., Arjmandi, B. H., Doctolero, S., and Wang, J. S. Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial. Osteoporos.Int. ;23(5):-. View abstract.

Shim, J. S., Kang, M. H., Kim, Y. H., Roh, J. K., Roberts, C., and Lee, I. P. Chemopreventive effect of green tea (Camellia sinensis) among cigarette smokers. Cancer Epidemiol Biomarkers Prev ;4(4):387-391. View abstract.

Shimizu, M., Fukutomi, Y., Ninomiya, M., Nagura, K., Kato, T., Araki, H., Suganuma, M., Fujiki, H., and Moriwaki, H. Green tea extracts for the prevention of metachronous colorectal adenomas: a pilot study. Cancer Epidemiol.Biomarkers Prev. ;17(11):-. View abstract.

Shin, D. M. Oral cancer prevention advances with a translational trial of green tea. Cancer Prev.Res.(Phila Pa) ;2(11):919-921. View abstract.

Simmonds, M. J., Minahan, C. L., and Sabapathy, S. Caffeine improves supramaximal cycling but not the rate of anaerobic energy release. Eur.J Appl Physiol ;109(2):287-295. View abstract.

Singh, R., Ahmed, S., Islam, N., Goldberg, V. M., and Haqqi, T. M. Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB. Arthritis Rheum. ;46(8):-. View abstract.

Singh, R., Ahmed, S., Malemud, C. J., Goldberg, V. M., and Haqqi, T. M. Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes. J Orthop.Res. ;21(1):102-109. View abstract.

Slivova, V., Zaloga, G., DeMichele, S. J., Mukerji, P., Huang, Y. S., Siddiqui, R., Harvey, K., Valachovicova, T., and Sliva, D. Green tea polyphenols modulate secretion of urokinase plasminogen activator (uPA) and inhibit invasive behavior of breast cancer cells. Nutr Cancer ;52(1):66-73. View abstract.

Smits, P., Temme, L., and Thien, T. The cardiovascular interaction between caffeine and nicotine in humans. Clin Pharmacol Ther ;54(2):194-204. View abstract.

Sommer, A. P. and Zhu, D. Green tea and red light--a powerful duo in skin rejuvenation. Photomed.Laser Surg. ;27(6):969-971. View abstract.

Sonoda, J., Koriyama, C., Yamamoto, S., Kozako, T., Li, H. C., Lema, C., Yashiki, S., Fujiyoshi, T., Yoshinaga, M., Nagata, Y., Akiba, S., Takezaki, T., Yamada, K., and Sonoda, S. HTLV-1 provirus load in peripheral blood lymphocytes of HTLV-1 carriers is diminished by green tea drinking. Cancer Sci ;95(7):596-601. View abstract.

Stingl, J. C., Ettrich, T., Muche, R., Wiedom, M., Brockmoller, J., Seeringer, A., and Seufferlein, T. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. BMC.Cancer ;11:360. View abstract.

Stockfleth, E., Beti, H., Orasan, R., Grigorian, F., Mescheder, A., Tawfik, H., and Thielert, C. Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial. Br.J Dermatol. ;158(6):-. View abstract.

Subramaniam, P., Eswara, U., and Maheshwar Reddy, K. R. Effect of different types of tea on Streptococcus mutans: an in vitro study. Indian J.Dent.Res. ;23(1):43-48. View abstract.

Sun, C. L., Yuan, J. M., Koh, W. P., and Yu, M. C. Green tea, black tea and colorectal cancer risk: a meta-analysis of epidemiologic studies. Carcinogenesis ;27(7):-. View abstract.

Sung, H., Min, W. K., Lee, W., Chun, S., Park, H., Lee, Y. W., Jang, S., and Lee, D. H. The effects of green tea ingestion over four weeks on atherosclerotic markers. Ann.Clin Biochem ;42(Pt 4):292-297. View abstract.

Takeshita M, Takashima S Harada U Shibata E Hosoya N Takase H et al. Effects of long-term consumption of tea catechins-enriched beverage with no caffeine on body composition in humans. Japanese Pharmacology and Therapeutics ;36(8):767-776.

Tang, N. P., Li, H., Qiu, Y. L., Zhou, G. M., and Ma, J. Tea consumption and risk of endometrial cancer: a metaanalysis. Am.J Obstet.Gynecol. ;201(6):605-608. View abstract.

Tang, N., Wu, Y., Zhou, B., Wang, B., and Yu, R. Green tea, black tea consumption and risk of lung cancer: a meta-analysis. Lung Cancer ;65(3):274-283. View abstract.

Tatti, S., Stockfleth, E., Beutner, K. R., Tawfik, H., Elsasser, U., Weyrauch, P., and Mescheder, A. Polyphenon E: a new treatment for external anogenital warts. Br.J Dermatol. ;162(1):176-184. View abstract.

Tatti, S., Swinehart, J. M., Thielert, C., Tawfik, H., Mescheder, A., and Beutner, K. R. Sinecatechins, a defined green tea extract, in the treatment of external anogenital warts: a randomized controlled trial. Obstet.Gynecol. ;111(6):-. View abstract.

Tomankova, K., Kolarova, H., Bajgar, R., Jirova, D., Kejlova, K., and Mosinger, J. Study of the photodynamic effect on the A549 cell line by atomic force microscopy and the influence of green tea extract on the production of reactive oxygen species. Ann.N.Y.Acad.Sci. ;:549-558. View abstract.

Tsao, A. S., Liu, D., Martin, J., Tang, X. M., Lee, J. J., El-Naggar, A. K., Wistuba, I., Culotta, K. S., Mao, L., Gillenwater, A., Sagesaka, Y. M., Hong, W. K., and Papadimitrakopoulou, V. Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions. Cancer Prev.Res.(Phila Pa) ;2(11):931-941. View abstract.

Tzellos, T. G., Sardeli, C., Lallas, A., Papazisis, G., Chourdakis, M., and Kouvelas, D. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis. J.Eur.Acad.Dermatol.Venereol. ;25(3):345-353. View abstract.

Ullmann, U., Haller, J., Decourt, J. D., Girault, J., Spitzer, V., and Weber, P. Plasma-kinetic characteristics of purified and isolated green tea catechin epigallocatechin gallate (EGCG) after 10 days repeated dosing in healthy volunteers. Int J Vitam.Nutr.Res. ;74(4):269-278. View abstract.

Unno, T., Kondo, K., Itakura, H., and Takeo, T. Analysis of (-)-epigallocatechin gallate in human serum obtained after ingesting green tea. Biosci.Biotechnol.Biochem ;60(12):-. View abstract.

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Wang, H., Wen, Y., Du, Y., Yan, X., Guo, H., Rycroft, J. A., Boon, N., Kovacs, E. M., and Mela, D. J. Effects of catechin enriched green tea on body composition. Obesity.(Silver.Spring) ;18(4):773-779. View abstract.

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Thanks to its content of beneficial compounds and antioxidants, green tea may offer several health benefits.

Helps Protect the Heart

&#;Green tea contains catechins, a type of flavonoid with potent antioxidant properties,&#; says Sam Schleiger, a functional medicine dietitian based in Elkhorn, Wisconsin and founder of the nutrition practice Simply Nourished. &#;These catechins help reduce the formation of plaques in the arteries, lower LDL (&#;bad&#;) cholesterol levels and improve blood lipid profiles, ultimately decreasing the risk of heart disease.&#;

These heart health benefits appear in research as well. According to one review of nine studies, people who drank one to three cups of green tea per day had a lower risk of stroke and heart attack. Additionally, people who consumed at least 10 cups per day had lower levels of LDL cholesterol compared to those who drank less than three cups daily . Similarly, a analysis of seven studies shows that drinking green tea may be linked to a lower risk of coronary heart disease .

May Support Weight Loss

Green tea contains compounds like caffeine and epigallocatechin gallate (EGCG), both of which may speed up metabolism and help break down fat cells, explains Amy Shapiro, a registered dietitian and founder of Real Nutrition NYC, a nutrition counseling practice. &#;Caffeine is a stimulant that has been shown to aid in fat burning and to improve exercise outcomes,&#; continues Shapiro. &#;It boosts the effects of some fat burning hormones like norepinephrine, which tells fat cells to release fat into the bloodstream to be used as energy instead of storing it.&#;

One study shows an association between green tea consumption and reductions in body weight, body mass index (BMI) and belly fat in individuals living with obesity . What&#;s more, another review concluded that green tea consumption has the potential to promote weight loss in women with polycystic ovary syndrome (PCOS), although researchers note the exact dosage of green tea that can cause this kind of weight loss has not been determined .

May Boost Brain Health

&#;Green tea contains caffeine, which can improve alertness, concentration and memory,&#; says Schleiger. &#;Additionally, it contains an amino acid called L-theanine that promotes relaxation and increases the production of neurotransmitters like dopamine and serotonin, leading to improved brain function,&#; she adds.

According to one review in Phytomedicine, green tea may offer several benefits for brain function, including helping decrease anxiety, improving memory and increasing attention . Although more research is needed, another review reports that certain compounds in green tea may even help treat or play a role in preventing neurodegenerative disorders like Alzheimer&#;s disease, thanks to its ability to neutralize free radicals, ease inflammation and block the build-up of specific types of protein in the brain .

May Help Stabilize Blood Sugar Levels

Some research suggests that green tea may help keep blood sugar levels steady. This could be due to its content of EGCG, which Shapiro explains, &#;seems to prevent the breakdown of starches, which leads to increased blood sugar.&#;

In short-term studies, drinking green tea helped decrease fasting blood sugar levels . Still, more studies are needed, as other research has found that green tea has no effect on long-term blood sugar control or insulin levels .

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